Sunekos vs Profhilo: Which is better?

Sunekos and Profhilo Skin Booster Treatment, West Malling, Kent and Marylebone London

When it comes to improving skin quality, hydration and elasticity, two of the most talked-about injectable treatments are Sunekos and Profhilo. Both are powerful skin boosters that can rejuvenate the skin from within, but they work in slightly different ways. Understanding those differences can help you decide which one might be best for your skin goals.

At first glance, Sunekos and Profhilo may seem similar. They both use injectable hyaluronic acid to hydrate and restore the skin, but each goes beyond simple moisturisation to trigger natural regeneration processes. The key lies in their formulations and the way they interact with your skin’s structure.

What is Profhilo?

Profhilo is often described as an injectable moisturiser, but that hardly does it justice. It contains one of the highest concentrations of pure hyaluronic acid available and is specially formulated to spread evenly beneath the skin. Rather than adding volume like a filler, Profhilo works by stimulating the production of collagen and elastin, helping to remodel the skin’s support structure and improve its overall tone and texture.

Once injected, Profhilo spreads through the skin tissue, providing deep hydration while gradually tightening and firming the skin over time. It is particularly effective for areas like the face, neck, décolletage and hands, where loss of elasticity and fine lines are most noticeable. Patients typically see their skin become smoother, firmer and more luminous after just two sessions spaced four weeks apart.

What is Sunekos?

Sunekos is another injectable treatment that focuses on regenerating the skin from within, but it has a slightly different composition and mode of action. It combines hyaluronic acid with a unique blend of amino acids – the building blocks of collagen and elastin. This combination stimulates fibroblasts in the skin to produce fresh collagen and elastin, leading to improved elasticity, hydration and structure.

Where Profhilo is designed to hydrate and tighten the skin more broadly, Sunekos excels in treating more delicate areas and improving fine lines and textural changes. It is often used under the eyes, where the skin is thinner and more prone to crepiness, as well as on the face, neck and hands. The amino acids in Sunekos make it particularly effective for restoring the extracellular matrix – the skin’s internal scaffolding – which helps improve overall firmness and resilience.

How do they differ?

The key difference between Sunekos and Profhilo lies in their formulations and how they target the skin’s biology. Profhilo uses a high concentration of stabilised hyaluronic acid to provide intense hydration and trigger collagen and elastin production. It works best for overall skin laxity, hydration and glow.

Sunekos, on the other hand, contains both hyaluronic acid and amino acids, offering a more targeted regenerative effect. It is ideal for areas that require structural improvement and for patients with thinner or more fragile skin.

Another practical difference is the treatment protocol. Profhilo typically requires two sessions one month apart, while Sunekos is usually performed as a course of four treatments spaced 7–10 days apart. Profhilo results tend to appear after the second session, while Sunekos builds gradually throughout the course, with results continuing to improve over the following months.

What are the results like?

Both treatments deliver natural-looking, subtle improvements rather than dramatic changes. With Profhilo, patients often describe their skin as looking firmer, lifted and more hydrated, with a noticeable radiance that develops over several weeks. It is particularly beneficial for those who feel their skin has lost elasticity or appears dull and tired.

Sunekos provides a similar glow but with added regeneration benefits. It is especially useful for improving skin texture, reducing fine lines and restoring elasticity in areas where the skin is thin or crepey. Around the eyes, where traditional fillers can be unsuitable for certain concerns, Sunekos offers a safe and effective alternative.

Can you combine Sunekos and Profhilo?

In many cases, combining Sunekos and Profhilo can produce even better results. Because they work in different but complementary ways, they can be used together to address multiple aspects of skin ageing. Profhilo hydrates and tightens the skin, while Sunekos rebuilds the deeper structural integrity. When used in combination, they create smoother, firmer and more radiant skin with improved long-term resilience.

The best approach depends on your skin type, age and specific concerns. For younger patients seeking prevention and hydration, Profhilo alone may be enough. For more mature or delicate skin showing signs of thinning, Sunekos may be the better starting point. In some cases, your practitioner may recommend alternating between the two treatments over time to maintain optimal skin health.

Are there any side effects?

Both Sunekos and Profhilo are very safe when performed by qualified medical practitioners. As they are made from naturally occurring substances, the risk of allergic reaction is extremely low. After treatment, you might experience mild redness, swelling or small bumps at the injection points, but these typically settle within 24 hours.

It is important to avoid strenuous exercise, heat exposure and applying makeup for 24 hours after your session to allow the skin to recover and for the product to integrate properly.

So, is there a better option?

The truth is, neither is objectively “better” than the other; it depends entirely on your skin and what you want to achieve. Profhilo is a brilliant option for those seeking an all-over lift, improved hydration and enhanced elasticity. Sunekos is ideal for targeting finer lines, delicate areas and skin that needs a deeper regenerative boost.

Both treatments deliver beautiful, natural results that enhance your skin’s own regenerative capabilities rather than changing your features. If you are unsure which one is right for you, a personalised consultation is the best place to start. Together, we can assess your skin, discuss your goals and create a tailored plan to restore your skin’s health, strength and radiance from within. If you’d like to understand what’s right for your skin, click here to book a consultation with an Illuminate Skin Clinic, Kent or London expert.