Does Zinc Really Make Botox Laser Longer?

Botox Treatment, West Malling, Kent

If you’ve had Botox before, or are considering it, you might have come across the idea that taking zinc can help it last longer. It’s a popular topic in the aesthetics world, especially among patients looking to maximise their results and stretch the time between appointments. But is there any truth to it?

Let’s break it down. What does the science say, and is zinc worth adding to your routine?

Where the idea comes from

The theory that zinc can enhance the effects of Botox stems from a small study published over a decade ago. Researchers found that patients who took a combination of zinc and an enzyme called phytase (in a supplement known as Zytaze) experienced a longer duration of results after their botulinum toxin injections, sometimes by up to 30%.

The reasoning? Zinc is thought to play a role in how botulinum toxin binds to nerve endings. In simple terms, botulinum toxin needs to connect with specific receptors in the body to block muscle movement. Zinc appears to be a co-factor in that process, potentially supporting a more efficient “uptake” of the treatment.

So, does it really work?

The answer is: possibly, but it’s not a guaranteed fix.

That initial study involved a very small group of people and used a specific combination of zinc and phytase, not just over-the-counter zinc supplements. More research is still needed to confirm how significant the effect is across a broader range of patients.

What we do know is that zinc deficiency may impair how your body responds to Botox, so if you’re already low in zinc (which some people are), supplementing could support more consistent results. On the other hand, if your zinc levels are already adequate, taking more might not make a noticeable difference.

It’s also worth noting that the formulation used in the study, Zytaze, isn’t widely available in the UK, and taking high doses of zinc without medical supervision isn’t recommended.

Should you take zinc before your Botox appointment?

If you’re curious about trying zinc to see if it helps your results, it’s best to do so in a considered, safe way. Speak to your practitioner first. We can help you assess whether a supplement might be beneficial based on your overall health, diet, and treatment goals.

A short course of zinc (around 50mg per day) taken for a few days before your Botox appointment may support your results, but again, it’s not a magic bullet, and it’s not essential for everyone.

What really makes Botox results last longer?

Zinc aside, there are a few well-established ways to get the most from your Botox:

• Stay consistent with your treatments. Regular appointments can help ‘train’ the muscles to stay more relaxed over time.
• Avoid strenuous activity, alcohol and excess heat for at least 24 hours after your treatment.
• Keep your skin healthy with good quality skincare and sun protection—UV damage can undermine all your aesthetic efforts.
• Work with a skilled, medically trained practitioner who understands facial anatomy and injects precisely where needed. Great technique is everything.

The bottom line

Zinc may offer a mild boost for some patients, especially if there’s a deficiency, but it’s not a miracle ingredient. If you’re already getting great results from your Botox and seeing it last around 3-4 months, zinc probably isn’t necessary. If your results fade more quickly than expected, it might be worth exploring under professional guidance.

At our clinic, we’ll always tailor your treatment based on your individual needs and talk through any supplements or steps that might enhance your outcome. If you have questions or want to make your next Botox treatment last as long as possible, we’re here to help.

If you’d to learn more about Botox, or to establish whether it’s the right treatment for you, click here to enquire or to book a consultation with an Illuminate Skin Clinic expert.