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Polynucleotides vs Exosomes: Which is right for you?
Blog
11 March 2025

Blog
11 March 2025
Polynucleotides, Exosomes Treatment, Kent and London
If you’ve been exploring the latest treatments to rejuvenate your skin or tackle early signs of ageing, you’ve probably come across exosomes and polynucleotides. These advanced therapies are making waves in aesthetics, offering fresh, science-backed ways to help you look and feel your best. But how do you know which one is right for you?
In this post, we’ll break down everything you need to know about exosome therapy and polynucleotide treatments—what they are, how they work, and what you can expect, so you can make an informed decision about what’s best for your skin.
What is exosome therapy?
Let’s start with exosomes. Think of these as tiny messengers naturally produced by your cells. Their job? To deliver important information that triggers cell repair, regeneration, and overall health.
In aesthetics, we use exosome therapy to rejuvenate skin, promote hair growth, and even speed up recovery after treatments like microneedling or lasers. These little powerhouse vesicles contain proteins, growth factors, and other active ingredients that help your skin repair itself from the inside out.
How exosomes work in aesthetics
Exosomes essentially give your cells a wake-up call. They communicate directly with your skin cells, encouraging them to produce more collagen, repair damage, and calm inflammation.
When combined with treatments like microneedling, exosomes penetrate deeper into your skin, maximising their effects. The result? Smoother, brighter, and more youthful-looking skin. They’re also an exciting option for those struggling with hair thinning, as they can stimulate hair follicles and promote healthier growth.
Who is a good candidate for exosome therapy?
Exosome therapy is great for anyone wanting a natural, non-invasive way to improve their skin or hair. It’s perfect if you’re noticing fine lines, uneven texture, or if your skin just needs a boost. For those looking to combat hair thinning, it’s a fantastic alternative to more invasive options.
If you’re someone who values treatments with minimal downtime and subtle, natural results, exosomes might be the solution you’ve been searching for.
What results can you expect?
Patience is key with exosomes. You’ll start to notice improvements in your skin’s texture and tone within a few weeks, and the benefits keep building over time. Think firmer, plumper, and more radiant skin, with reduced fine lines and a healthier overall glow.
For hair restoration, results tend to develop gradually. Over several months, you may notice thicker, fuller hair and less shedding. It’s all about delivering steady, long-term improvements.
What are polynucleotides?
Now, let’s talk polynucleotides. These are DNA fragments that work wonders for your skin’s hydration and repair processes. They’re like the ultimate skin rescue treatment, focusing on deep hydration, rebuilding the skin’s structure, and protecting against damage.
Unlike exosomes, which signal your cells to regenerate, polynucleotides physically rebuild and repair your skin’s foundation. This makes them especially useful for skin that’s dry, damaged, or showing signs of stress and ageing.
How polynucleotides work
Polynucleotides bind to water molecules in your skin, creating a hydrating and plumping effect. But that’s not all—they also stimulate collagen production and protect your skin from free radicals, slowing down the ageing process.
By working deep within the extracellular matrix (the supportive structure of your skin), polynucleotides help repair damage, improve elasticity, and give your skin that fresh, rejuvenated look.
Who is a good candidate for polynucleotide treatments?
If your skin feels dull, dehydrated, or has lost some of its bounce, polynucleotides could be your new go-to. They’re particularly effective for treating fine lines, wrinkles, pigmentation, and scars, making them a versatile choice for many skin types.
This treatment is also ideal if you’ve been dealing with sun damage or if your skin has taken a hit from environmental stressors like pollution. It’s all about restoring and strengthening your skin’s natural structure.
What results can you expect?
Polynucleotide treatments deliver a hydration boost that’s hard to match. Your skin will feel plumper, smoother, and more elastic within weeks of treatment. Over time, you’ll notice a brighter, healthier complexion, with scars and fine lines becoming less noticeable.
The effects are subtle yet powerful, leaving your skin looking naturally refreshed and glowing.
Exosomes vs polynucleotides: Which one’s for you?
Both exosomes and polynucleotides offer fantastic results, but the right choice depends on your skin goals.
Exosomes are your pick if you’re after cellular-level repair and regeneration. They’re brilliant for anti-ageing, improving skin vitality, and even promoting hair growth. If you want to supercharge your skin’s natural healing process, exosomes are a standout option.
Polynucleotides are perfect for deep hydration, repairing damaged skin, improving pigmentation, dark circles or scarring and enhancing elasticity. They’re especially effective for dry, stressed, or mature skin, offering long-lasting hydration and support.
The best part? These treatments can complement each other. While exosomes rejuvenate from the inside out, polynucleotides focus on repairing and hydrating, giving you a comprehensive approach to skin health.
So, which one is right for you?
If you’re still unsure, don’t worry. It’s always best to have a consultation with an experienced practitioner who can assess your skin and help you decide. Whether you choose exosomes, polynucleotides, or a combination of both, you can trust that these advanced treatments will help you achieve a glowing, rejuvenated look.
Your skin is unique, and your treatment plan should be too. So take the time to explore your options and work with a professional to find what works best for you.
If you’d like to learn more about the options, or to establish what’s right for you, click here to enquire or to book a consultation with an Illuminate Skin Clinic, Kent and London, expert.
Disclaimer: Please be aware that results and benefits may vary from patient to patient taking into consideration factors such as age, lifestyle and medical history.