Does NAD+ reverse ageing?

Our levels of NAD⁺ dramatically decrease as we grow older. In fact, our NAD+ levels decrease by 50% every 20 years from the age of 20. By 80, NAD⁺ levels can be around just 5% of that when we were in our prime. NAD⁺ helps manage our ageing process, as well as decreasing other important ageing elements including DNA damage and illness. Maintaining our NAD+ levels can effectively reduce our biological age – the rate at which you are ageing on the inside. Unlike your chronological age, your biological age is very flexible, and studies show diet, physical activity, sleep, stress management and supplementation all contribute to improving your biological age.

Biological age: Are you ageing faster on the inside?

Biological age reflects your internal aging process, representing the state of your cellular function and the extent of accumulated damage. Research demonstrates that it serves as a reliable predictor of your future health, with a biological age surpassing your chronological age (the number of years since your birth) signifying an accelerated ageing trajectory. The good news is that your biological age can be reversed, and approximately 80% of it is influenced by lifestyle choices, meaning that modifications to your daily habits can reduce your biological age significantly.

Lifestyle practices such as physical activity, intermittent fasting, optimising sleep, reducing stress, and exposure to hot and cold conditions can induce changes in the epigenetic patterns of your cells, activating pathways that support repair and regeneration.

How to effectively boost your NAD+ levels

Exercise

Working out can boost your NAD⁺ levels naturally, according to studies. Scientists found that 12 weeks of aerobic training of 180 minutes per week increased NAD⁺ by 28 per cent in people aged over 35.

Not only does exercise boost NAD⁺ but it means your muscle mass functions well, so you’re less likely to have falls or become frail as you age. It also improves cardiovascular fitness, which is a massive predictor of age-related decline.

Consume polyphenols

Eating polyphenols from vegetables, fruit and olive oil helps you to age better, because of their antioxidant and anti-inflammatory properties, which reduce the risk of cardiovascular disease, stroke and cancer. The best sources of polyphenols include berries, beans, hazelnuts, pecans, plums, dark chocolate, spinach and green tea.

Sleep well

During sleep your body repairs cellular damage in the skin, brain and muscles. Researchers found just a single night of poor sleep can make cells age more quickly in older adults. You can improve your changes of ageing well by aiming to get 7-8 hours of high quality sleep a night.

Socialise 

People who have frequent positive social interactions have lower levels of inflammatory molecule interleukin-6, which has been implicated in age-related disorders such as Alzheimer’s, osteoporosis, heart disease and cancer.

Reduce stress

While short term cellular stress such as exercise is beneficial for your cells, chronic psychological stress can increase inflammation and negatively impact your biological age. Multiple studies show that traumatic stress experienced at any age can increase biological age and influence the rate of ageing during later life. Incorporating stress management techniques which support your mental health such as journaling, mediation or breathing exercises can all help to reverse biological age.

Supplement

Changes in NAD⁺ levels have been shown to be involved in the ageing process. NAD⁺ is essential for cellular health because of its critical role in the production of cellular energy. As NAD⁺ levels decline during ageing our cells stop producing sufficient energy and cannot perform critical functions. NAD⁺ also powers cellular repair and regeneration and without these pathways being switched on, damage accumulates accelerating the ageing process.

Given the many important functions of NAD⁺, it is unsurprising that increasing NAD⁺ levels has been shown to reverse biological age. In clinical trials, Nuchido TIME+ – our preferred NAD⁺ supplement – increased NAD⁺ levels, reduced inflammation, activated healthy ageing proteins and reduced biological age by 1.26 years in just 28 days.

If you’d like to learn more about Nuchido TIME+, click here to enquire or to purchase.

Disclaimer: Please be aware that results and benefits may vary from patient to patient taking into consideration factors such as age, lifestyle and medical history.